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Stachybotrys sp.

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Aw (water activity) - 0.94, optimum Aw (water activity) - >0.98. Several strains of this fungus (S. atra, S. chartarum and S. alternans are synonymous) may produce a trichothecene mycotoxin- Satratoxin H - which is poisonous by inhalation. The toxins are present on the fungal spores. This is a slow growing fungus on media. It does not compete well with other rapidly growing fungi. The dark colored fungi grows on building material with a high cellulose content and a low nitrogen content. Areas with relative humidity above 55% and are subject to temperature fluctuations are ideal for toxin production. Individuals with chronic exposure to the toxin produced by this fungus reported cold and flu symptoms, sore throats, diarrhea, headaches, fatigue, dermatitis, intermittent local hair loss, and generalized malaise. The toxins produced by this fungus will suppress the immune system affecting the lymphoid tissue and the bone marrow. Animals injected with the toxin from this fungus exhibited the following symptoms: necrosis and hemorrhage within the brain, thymus, spleen, intestine, lung, heart, lymph node, liver, and kidney. The mycotoxin is also reported to be a liver and kidney carcinogen. Affects by absorption of the toxin in the human lung are known as pneumomycosis. This organism is rarely found in outdoor samples. It is usually difficult to find in indoor air samples unless it is physically disturbed. The spores are in a gelatinous mass. Appropriate media for the growth of this organism will have a high cellulose content and a low nitrogen content. The spores will die readily after release. The dead spores are still allergenic and toxigenic. Percutaneous absorption has caused mild symptoms.

Strachybotrys is a fungus which is most of the times marooned as a contaminant for both in and outdoors.  It does well in areas where there are a lot of cellulose and low amounts of nitrogen. It can also be found in decomposing hay, leaves seeds, on soil and water damaged buildings. It belongs to the stachy genus and has one species stachybotrys chartarum which is well known.

Stachybotrys sp.

 

 

 

 

 

 

 

The fungus produces cottony fast growing colonies which mature within four days. From the front and back it is white in color and changes to black as it becomes older. It has the following microscopic features: Separate hyphae which appears the first and has dark pigments as they come of age. Conidiophores which bear phialides as their apices and may either be simple or branched, like the hyphaes. 

They also appear first and darken as they age. Phialides which are circular, have swollen upper portions, form clusters of tree to ten and are either pigmented or hyaline. Conidia are one celled, found in clusters, are oval in shape and are either pigmented or hyaline. When dealing with this fungi you do not need special precautions to deal wit it, you only need to follow common laboratories rules. Strachybotrys produces trichothecene mycotoxins which are potential inhibitors of DNA, RNA and protein synthesis.

They spark inflammatory reactions and disfigure the alveolar concentrations. The toxins get to the human body through experiments, eating food that is contaminated with the fungi or by inhaling the fungi directly. The existence of the stachybotrys fungi was first seen in cattle and horses in Russia. They caused several disorders such as rhinitis and neurological disorders after the animals ate hay which was contaminated by the fungi. This outbreak caused attention to be drawn to the stachybotrys fungi and its toxins. It was also known that it caused the Yellow rain attacks in Asia by the use of trichothecenes as agents of biologic warfare.  

After this many animal tests were done to show the effects of trichothecenes. A test was done on mice and it was discovered that the toxins in stachybotrys can be produced or get airborne on special environmental setting.

Stachybotrys has been of keen interest to health workers because of two major reasons. One main reason is that it is one of the leading contaminants attacking buildings that cause major problems in the system design and operational strategies leading to increased levels in indoor moisture leading to a syndrome known as “sick building”. This can also occur due to the infestation of molds and other fungi such as Penicillin and Cladosporium. The increased level of moisture has lead to the damaging of interior surfaces and can lead to human beings being exposed to the risk of getting asthma and lung diseases.

The second reason why stachybotrys is of importance to health workers is the fact that it leads to the development of acute pulmonary hemorrhage and hemosides in children. The fungus was cultivated in water damaged houses where the toxins make the children's capillaries to be more fragile.