The Conidiobolus sp. of fungus is isolated from insects, amphibians, soil as well as decaying plant matter. It is usually found in tropical areas, such as the rainforests of central America; it was also discovered to be present in India and equatorial Africa. Several species fall under the genus Conidiobolus, and the most common ones include Conidiobolus coronatus, Conidiobolus incongruus and Conidiobolus lamprauges.

The Conidiobolus sp. has been identified as a cause of infection for animals (deer, dogs, horses and sheep) and humans alike. The most common infection linked to Conidiobolus sp. in humans is that which affects the nasal mucosa and maxillofacial tissues. Entomophthoromycosis conidiobolae is the chronic inflammatory disease that is caused by Conidiobolus sp. Resulting in the formation of subcutaneous nodules or polyps, this infection can be acquired either by an insect bite or through inhalation. Healthy persons working outdoors in tropical environments are most at risk.