Aspergillus puniceus is not considered common indoors. Its natural habitat is that of soil where it is usually isolated from. The lack of data regarding the isolation of this mold may be due in part to the fact that it is not as common as other types of aspergillus molds. However, studies have shown that such mold type is allergenic.

Due to the lack of extensive studies concerning Aspergillus puniceus, there is still no evidence about how it can affect the health of humans and animals. Therefore, people should be careful when handling this type of mold since there is no proof if it's a health hazard, although there are no documented cases of invasive illnesses associated with it.